Dynamic visual tests: temporal aspects of visual perception in demyelinative diseases
In recent years, we have witnessed a blossoming in the field of visual measures in multiple sclerosis (MS). I will argue that numerous visual and vision-related methods can be used to study axonal and demyelinating aspects of the disease.
Special attention will be given to the temporal aspects of visual perception following optic neuritis. To that end, we demonstrated a persistent motion perception deficit in these patients (Raz et al. Neurology, 2011) and suggested that demyelination was probably the cause for these temporal deficits of perception (Raz et al. Annals of Neurology, 2012). Furthermore, studying the fellow clinically unaffected eye of optic neuritis patients, we argue that visual projection via this eye reflects an adaptive process. Additionally, these binocular changes offered a functional advantage; synchronization of inputs resulted in improved dynamic 3-dimentional perception.
Thus, while results in the affected eyes, highlight the need for rapid transmission of visual input to perceive motion, the results in the fellow eyes reflect an adaptive process aimed at binocular integration in time, to adjust the damage incurred. This adaptation contributes to temporal synchronization of binocular visual information and improves binocular visual functions (Raz et al. Neurology, 2013, Benoliel T., MS journal, 2017).